Support healthy immune cell activity today!

QTY - 30 Vegetarian Capsules

Immune-Up  

• Supports Healthy Immune Function*
• Supports the Body’s Defenses Against Seasonal Immune Challenges*
• Active Ingredient Beta-Glucan 

Science 

Bock Nutritionals’s Immune-Up is refined to remove most impurities, including proteins and fats that can interfere with uptake and effectiveness.

Beta-glucan has been recognized for its support of immune system activity for centuries[1]; and yeast-derived beta-glucan has become the subject of over 800 scientific studies to date. Bock Nutritionals Immune-Up contains concentrated 1,3/1,6 beta-glucan from the yeast Saccharomyces cerevisiae, a source known to support immune function. [2-4] Beta-glucan is produced by fungi, grains, seaweed, and yeast, but not by mammalian cells.[3-5] delivers 250 mg of whole glucan particle per capsule, providing beta 1,3/1,6 glucan—a unique complex carbohydrate purified from Saccharomyces cerevisiae (baker’s yeast).

It is natural, non-genetically modified (non-GMO), hypoallergenic, patented, and generally recognized as safe (GRAS). Taken orally, Immune-Up primes and mobilizes the cells that support the body's first-line immune response.*

• Non-GMO
• Hypoallergenic
• GRAS

Supplement Facts

Suggested Use: For ongoing immune support: Take 1 capsule daily, first thing in the morning or last thing at night (before or well after a meal), with a full 8 oz glass of water. For fast-acting immune support: Take up to 2 capsules per day, as above; or as directed by your healthcare practitioner.* 

Servings Per Container: 30

Serving Size: 1 Capsule

Other Ingredients: Dicalcium phosphate anhydrous, HPMC (capsule), stearic acid, magnesium stearate, silica, and medium-chain triglycerides. 

FORMULATED TO EXCLUDE: Wheat, gluten, corn, yeast protein, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.

 References 

1. Tian J, Ma J, Wang S, et al. Increased expression of mGITRL on D2SC/1 cells by particulate β-glucan impairs the suppressive effect of CD4(+)CD25(+) regulatory T cells and enhances the effector T cell proliferation. Cell Immunol. 2011 May 10;270(2):183-7. [PMID: 21636079]
2. 2. Feldman S, Schwartz HI, Kalman DS, et al. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. J Appl Res. 2009 MarchJune;9(1&2):30-42. http://jrnlappliedresearch.com/articles/Vol9Iss1/FeldmanVol9No1.pdf. Accessed September 9, 2011.
3. 3. Driscoll M, Hansen R, Ding C, et al. Therapeutic potential of various beta-glucan sources in conjunction with anti-tumor monoclonal antibody in cancer therapy. Cancer Biol Ther. 2009 Feb;8(3):218-25. [PMID: 19106638]
4. 4. Liang, J., D. et al. Enhanced clearance of a multiple antibiotic-resistant Staphylococcus aureus in rats treated with PGG-glucan is associated with increased leukocyte counts and increased neutrophil oxidative burst activity. Int J Immunopharmacol. 1998 Nov;20(11):595-614. [PMID: 9848393]
5. 5. Vetvicka V. Glucan-immunostimulant, adjuvant, potential drug. World J Clin Oncol. 2011 Feb 10;2(2):115-9. [PMID: 21603320]
6.  Vetvicka V, Terayama K, Mandeville R, et al. Pilot study: orally-administered yeast ß1,3-glucan prophylactically protects against anthrax infection and cancer in mice. JANA. 2002;5(2):5-9. Reprint. http://www.ana-jana.org/Journal/journals/JANAVol52.pdf. Accessed August 21.
7. 7. Natural Standard Database http://naturalstandard.com. Accessed July 23, 2011.
8.  Yan J, Allendorf DJ, Brandley B. Yeast whole glucan particle (WGP) beta-glucan in conjunction with antitumour monoclonal antibodies to treat cancer. Expert Opin. Biol Ther. 2005 May;5(5):691-702. [PMID: 15934844]
9. 9. Qi C, Cai Y, Gunn L, et al. Differential pathways regulating innate and adaptive antitumor immune responses by particulate and soluble yeast-derived ß-glucans. Blood. 2011 Jun 23;117(25):6825-36. [PMID: 21531981]
10. 10. Pelizon AC, Kaneno R, Soares AM, et al. Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae. Physiol Res. 2005;54(5):557-64. [PMID: 16238470]
11. 11. Tsikitis V, Albina J, Reichner J. Beta-glucan affects leukocyte navigation in a complex chemotactic ingredient. Surgery. 2004 Aug;136(2):384-9. [PMID: 15300205]
12. 12. Senoglu N, Yuzbasioglu MF, Aral M, et al. Protective effects of N-acetylcysteine and beta-glucan pretreatment on oxidative stress in cecal ligation and puncture model of sepsis. J Invest Surg. 2008 Sep-Oct;21(5):237-43. [PMID: 19160131]
13. 13. Turnbull, JL, Patchen ML, Scadden DT. The polysaccharide, PGGglucan, enhances human myelopoiesis by direct action independent of and additive to early-acting cytokines. Acta Haematol. 1999;102(2):66-71. [PMID: 10529508]
14. 14. Kournikakis B, Mandeville R, Brousseau P, et al. Anthrax-protective effects of yeast beta 1,3 glucans Med Gen Med. 2003 Mar 21;5(1):1. [PMID:12827062]